Thalidomide
immunomodulatory drug known for its ability to cause birth defects
Common Themes
Videos Mentioning Thalidomide
#140 - Gerald Shulman, MD, PhD: Insulin resistance—molecular mechanisms and clinical implications
Peter Attia MD
A drug that was famously pulled by the FDA, being the second major act after DNP, but is now back in clinical use for specific indications.
The Causes & Treatments for Autism | Dr. Karen Parker
Andrew Huberman
A morning sickness medication that caused profound limb abnormalities in children, as toxicity testing was done only in mice and not in primates like marmosets.
How to Embrace Slow Productivity, Achieve Mastery, and Defend Your Time — Cal Newport & Tim Ferriss
Tim Ferriss
Drug that caused severe birth defects, used as an analogy for how new technologies should be treated like new drugs, with caution and long-term evaluation.
#71 – Katherine Eban: Widespread fraud in the generic drug industry
Peter Attia MD
A drug widely dispensed in Europe in the early 1960s to pregnant women for morning sickness, but refused approval by the fledgling FDA in the US due to safety concerns, as it was later associated with severe birth defects.
How to Safeguard Your Hormone Health & Fertility | Dr. Shanna Swan
Andrew Huberman
A drug that caused severe limb development changes in babies, mentioned as an example of a chemical-induced syndrome.
#05 - Dom D’Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer
Peter Attia MD
An example of a pharmaceutical that caused problems due to using the wrong enantiomer.
AMA #3: supplements, women’s health, patient care, and more (EP.26) | The Peter Attia Drive
Peter Attia MD
A drug whose historical issues with birth defects led to a long period where women were virtually excluded from medical studies.
Chuck Palahniuk — A Masterclass in Creative Living and Dangerous Writing | The Tim Ferriss Show
Tim Ferriss
A drug prescribed in the mid-20th century, often to pregnant women, that had severe teratogenic effects, which was a cultural backdrop for discussions around medical control and reproductive rights.
Dr Andrew Weil — Optimal Health, Plant Medicine, and More | The Tim Ferriss Show (Podcast)
Tim Ferriss
A sedative drug, mentioned as a point in time before FDA regulations on experimental drug use became stricter.
Curing Autism, Epilepsy & Schizophrenia with Stem Cells | Dr. Sergiu Pașca
Andrew Huberman
A drug previously prescribed to pregnant mothers to prevent miscarriage, known to increase the risk for autism and cause major birth defects.