Uric acid
end product of nucleic acid degradation
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Videos Mentioning Uric acid
How Fructose Drives Metabolic Disease | Rick Johnson, M.D.
Peter Attia MD
The end product of purine metabolism, generated from ATP breakdown during fructose metabolism. High intracellular uric acid causes mitochondrial oxidative stress, inhibiting ATP production and stimulating fat storage.
How Sugar & Processed Foods Impact Your Health | Dr. Robert Lustig
Andrew Huberman
A byproduct of ATP metabolism that can inhibit mitochondrial function and endothelial nitric oxide synthase, leading to higher blood pressure.
Results from Peter's 3 week "nothingburger" (1 week keto—1 week fast—1 week keto) (AMA #2)
Peter Attia MD
A metric the speaker is maniacal about keeping low (below 5) due to its impact on blood pressure and atherosclerosis. It spiked significantly after the fast.
#14 – Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system
Peter Attia MD
A byproduct of fructose metabolism in the liver, its levels in the blood can be a proxy for fructose consumption and are linked to hypertension and stroke risk.
334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, and more
Peter Attia MD
Mentioned as another metabolite that could irritate arteries in conditions like chronic kidney disease, potentially contributing to atherosclerosis.