NMDA receptor
The primary receptor targeted by ketamine, differentiating it from classical psychedelics that act on serotonin receptors.
Common Themes
Videos Mentioning NMDA receptor

So I Tried Ketamine… | Bryan Johnson Podcast
Bryan Johnson
The primary receptor targeted by ketamine, differentiating it from classical psychedelics that act on serotonin receptors.

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
A receptor critical for neuroplasticity and brain changes, which ketamine blocks. Its activation acts as an 'and gate,' requiring high/unusual electrical activity and glutamate.

The Possibilities of Mind-Altering Compounds | Dr. Suresh Muthukumaraswamy | The Tim Ferriss Show
Tim Ferriss
A glutamate receptor heavily involved in neuroplasticity and long-term potentiation, which ketamine antagonizes. Its interaction with this receptor is a key focus in understanding ketamine's effects.

Erasing Fears & Traumas Based on the Modern Neuroscience of Fear
Andrew Huberman
A docking site on a neuron that, when strongly activated by intense events, initiates a cascade of signals within neurons, changing gene expression and increasing communication efficiency, crucial for new associations and fear learning.

Understand and Use Dreams to Learn and Forget | Huberman Lab Essentials
Andrew Huberman
N-methyl-D-aspartate receptor, a receptor in neurons that, when disrupted by ketamine, blocks long-term potentiation and changes in brain connectivity.

Understanding & Conquering Depression
Andrew Huberman
N-methyl D-aspartate receptor, a critical gate for neuroplasticity that is modulated by the phosphocreatine system and targeted by novel antidepressants like ketamine and PCP.

Understand and Use Dreams to Learn and Forget
Andrew Huberman
A receptor in the brain, gated by intense experience, that plays a role in long-term potentiation and learning; blocked by ketamine.

Rethinking Psychedelics, Octopuses on MDMA, and The Master Key of Metaplasticity | Dr. Gül Dölen
Tim Ferriss
A fast neurotransmitter receptor, blocked by magnesium, serving as a natural coincidence detector crucial for memory encoding, and whose subunit composition changes during critical periods.

220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.
Peter Attia MD
The N-methyl-D-aspartate receptor, an ionotropic glutamate receptor crucial for learning and memory processes like long-term potentiation. Ketamine's primary action is on this receptor, blocking glutamate transmission effectively.