D614G mutation

Concept

A specific mutation in the SARS-CoV-2 spike protein that disrupts a highly conserved nucleotide position, leading to a new adaptation for human-to-human transmission, observed to increase significantly in frequency.

Mentioned in 1 video

Videos Mentioning D614G mutation

Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113

Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113

Lex Fridman

A specific mutation in the SARS-CoV-2 spike protein that disrupts a highly conserved nucleotide position, leading to a new adaptation for human-to-human transmission, observed to increase significantly in frequency.