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Loonshots How to Nurture the Crazy Ideas with Safi Bahcall

T
The Innovation Show with Aidan McCullen
Science & Technology6 min read68 min video
Apr 20, 2019|1,712 views|13|3
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TL;DR

Radical breakthroughs like revolutionary cancer drugs and life-saving technologies often start as crazy ideas but fail because organizations can't balance nurturing artists with mobilizing soldiers.

Key Insights

1

Teams and companies experience phase transitions, suddenly shifting from embracing new ideas to rigidly rejecting them, similar to water freezing into ice, driven by underlying incentive structures rather than just culture.

2

The success of groundbreaking innovations like cancer drug 'Miller's Piranha' (which sold for $21 billion) and technologies like radar, which turned the tide of WWII, often involves navigating initial skepticism and perceived flaws.

3

Vannevar Bush's system for rapid innovation during WWII, which enabled the US to catch up with and surpass Nazi Germany's technology, is summarized by three principles: separating artists and soldiers ('the ice cube'), managing the transfer between them ('the garden hoe'), and loving both equally ('the heart').

4

Sir James Black's advice suggests that a true breakthrough drug is one that has been 'killed three times,' highlighting that persistent innovation often requires overcoming multiple failures, contrary to the 'fail fast and pivot' mantra.

5

The LSC (Listen to the Suck with Curiosity) mindset, exemplified by Judah Folkman, is crucial for innovators to extract valuable insights from rejection and criticism, rather than dismissing feedback defensively.

6

Steve Jobs' initial failure with the Macintosh project stemmed from creating hostility between 'artists' (innovators) and 'soldiers' (franchise managers), but upon his return to Apple, he successfully balanced these groups, demonstrating a 'gardener' leadership style.

The 'loonshot' phenomenon: high-risk, high-reward breakthroughs

The book "Loonshots" explores how groundbreaking innovations, often dismissed as crazy ideas initially, can become world-changing successes. A prime example is Richard Miller, an oncologist who developed 'Miller's Piranha,' a cancer drug so aggressive it violated conventional drug development wisdom. Despite initial rejection, clinical trials showed a response rate ten times higher than standard chemotherapy, leading to his company's $21 billion acquisition. This illustrates the 'loonshot' concept: an idea that is initially deemed unworkable or radical but possesses the potential for immense impact. The challenge for organizations is not just generating these ideas but also cultivating the environment for them to mature and succeed.

Phase transitions: the shift from embracing to rejecting ideas

Teams, companies, and even empires undergo 'phase transitions,' akin to water freezing into ice. Initially, small groups or nascent organizations are liquid-like, embracing wild new ideas. However, as they grow, their incentives shift. In small teams, individuals are highly aligned, with personal success tied directly to the idea's triumph – failure means widespread unemployment. In large organizations, individuals might prioritize career advancement within the hierarchy, leading them to reject novel ideas that don't immediately serve their rank or established goals. This shift from liquidity to solidity makes organizations rigid and resistant to innovation. The underlying incentive structures, not just a nebulous 'culture,' dictate this transition.

Structure over culture: controlling the shift in behavior

The author argues that structure, rather than culture, is the more effective lever for managing innovation and phase transitions. Culture is seen as the observable patterns of behavior (e.g., innovative vs. political), while structure refers to the underlying incentives and systems. Just as temperature controls whether water is liquid or solid, changing incentives can alter group behavior. Rewarding rank and hierarchy can lead to a political culture, where individuals suppress others' ideas to climb the ladder. Conversely, rewarding results and the pursuit of new ideas fosters an innovative culture. This principle is illustrated by Nokia's downfall: despite a lauded culture, its rigid structure led it to reject the smartphone and app store ideas, ultimately costing it its market dominance and trillions in market value.

The artists and the soldiers: separating and integrating innovation efforts

Vannevar Bush's approach to mobilizing scientific innovation during World War II provides a powerful framework. Bush recognized that radical innovation requires 'artists' (scientists and inventors) and that these groups are fundamentally different from 'soldiers' (military personnel focused on execution and deployment). The key was to separate these phases: an 'ice cube' approach. Artists work on developing novel technologies, while soldiers focus on manufacturing, scaling, and implementing them. Bush managed the transfer between these groups, not by dictating technology but by fostering communication and understanding – acting like a 'gardener' rather than a 'Moses' who anoints a single project. This distinction prevented the rigid military bureaucracy from stifling nascent technologies like radar, which was initially rejected by the US Navy for over a decade.

The three principles for nurturing loonshots

Bush's success can be distilled into three core principles: 1. The Ice Cube: Separate your artists and soldiers because they speak different languages and have different incentives. 2. The Garden Hoe: Lead like a gardener, managing the transfer and balance between these groups, rather than like Moses, anointing a single project. Focus on enabling communication and transition. 3. The Heart: Love your artists and soldiers equally. This means trusting and respecting both groups, valuing their contributions, and fostering an environment of mutual regard. This was crucial for Bush's success, as many others had tried and failed to influence the military before him. This principle underscores that effective leadership requires an appreciation for both the radical idea generators and the pragmatic executors.

The long road to success: overcoming 'three deaths'

True innovation often involves persistent failure, contrary to the popular 'fail fast and pivot' mantra. Nobel laureate Sir James Black advised that a drug isn't truly promising unless it has been 'killed three times.' This means facing significant setbacks and overcoming them. The development of statins, drugs that lower cholesterol, illustrates this: initial trials failed to show dietary changes worked, leading many to abandon the idea. Akira Endo persisted, identifying a potential drug, but faced hurdles: it didn't work in mice (due to their lack of LDL cholesterol), and early human trials showed potential cancer risks in dogs. Each of these was a 'death.' Only by persisting through these seemingly fatal flaws was the path cleared for statins to save millions of lives. This highlights the importance of deep commitment and the ability to learn from, rather than abandon, repeated failures.

Listen to the suck with curiosity: extracting value from criticism

Innovators must adopt an LSC – 'Listen to the Suck with Curiosity' – mindset. When faced with rejection or criticism, the natural reaction is defensiveness. However, highly successful innovators like Judah Folkman, who pioneered anti-angiogenesis therapy for cancer, actively sought to understand the 'suck.' When his research was questioned or failed to be reproduced, Folkman didn't become angry; he investigated. He discovered issues with experimental methodology, like shipping his drug improperly. This curiosity allows innovators to uncover flaws in their approach, customer perception, or market understanding that are hidden within the negative feedback. Dismissing criticism means missing potential 'gold nuggets' of insight crucial for refining and ultimately achieving breakthroughs.

Steve Jobs' evolution: from 'Moses' to 'gardener' led balanced teams

The popular narrative of Steve Jobs as a solitary visionary anointing successful projects hides a crucial lesson about leadership and phase transitions. Early Jobs, as 'Moses,' created division by labeling his innovative 'artists' as superior to the 'soldiers' working on legacy products. This hostility led to internal conflict, departures, and the failure of projects like the Macintosh. Upon his return to Apple, Jobs transformed into a 'gardener.' He appointed leaders like Jony Ive (artist) and Tim Cook (soldier) and challenged both groups intensely but with equal respect. He balanced the 'artists' and the 'soldiers,' recognizing the necessity of both to drive innovation from concept to product. His later success validates this balanced, inclusive approach, where both the dreamers and the doers are equally valued and nurtured.

Common Questions

A loonshot is a crazy idea that everyone says will never work but ultimately turns out to be very important. These radical breakthroughs often start with lone inventors like Richard Miller but require large groups to translate into successful products.

Topics

Mentioned in this video

People
Richard Miller

A Stanford professor and oncologist who developed a novel cancer drug that initially faced rejection but proved highly effective.

Steve Jobs

Co-founder of Apple, initially led with a 'Moses' style that created division and a failed Macintosh launch, but later succeeded by balancing artists and soldiers.

Vannevar Bush

Dean of Engineering at MIT who proposed a system to mobilize scientists for WWII, creating innovative technologies that turned the war's course.

Franklin Roosevelt

US President during WWII who met with Vannevar Bush and authorized the creation of a new group to mobilize the nation's scientists for the war effort.

Highland and Young

Two scientists working in the US Navy who discovered the principles of radar for detecting ships and planes but had their ideas rejected for years.

Karl Dönitz

Admiral of the German Navy who ordered the withdrawal of U-boats in March 1943 after significant losses due to Allied innovations like microwave radar.

Theodore Vail

A figure from whom Vannevar Bush drew inspiration for his innovation framework, particularly the idea of separating different types of teams and managing their transition, also known for his work with AT&T.

Judah Folkman

A physician and scientist who proposed blocking blood vessel growth to treat cancer, persisting through 30 years of ridicule and rejected grants, embodying the 'Listen to the Suck with Curiosity' principle.

Steve Wozniak

Co-founder of Apple along with Steve Jobs, who worked on the Apple II and later the franchise projects that faced hostility from Jobs' Macintosh team.

Tim Cook

Appointed by Steve Jobs to lead operations upon his return to Apple, known for his efficiency and often compared to a 'soldier' figure in business.

Safi Bahcall

Author of 'Loonshots', scientist, and entrepreneur, who explains the principles of nurturing radical breakthroughs by understanding phase transitions in human behavior and organizations.

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