Dopamine
Supplement
Mentioned in the context of effort and motivation, with the speaker clarifying it's more about effort than reward, and that animals can find things rewarding without dopamine.
Mentioned in 2 videos
Videos Mentioning Dopamine

Lisa Feldman Barrett: How the Brain Creates Emotions | MIT Artificial General Intelligence (AGI)
Lex Fridman
Mentioned in the context of effort and motivation, with the speaker clarifying it's more about effort than reward, and that animals can find things rewarding without dopamine.

How Your Brain Works & Changes | Huberman Lab Essentials
Andrew Huberman
A neuromodulator discussed as a molecule of motivation and reward, influencing mood and pursuit of external goals. It is released in smaller amounts when working towards a goal and can be excessively released in states like mania.