Phineas Gage
A historical case study in neuroscience of a railroad worker who survived a tamping iron destroying his orbital frontal prefrontal cortex, leading to a loss of ability to adjust behavior according to context.
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Videos Mentioning Phineas Gage

249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more
Peter Attia MD
A historical case study in neuroscience of a railroad worker who survived a tamping iron destroying his orbital frontal prefrontal cortex, leading to a loss of ability to adjust behavior according to context.

Life After Death? - The Shocking Proof You’re in a Simulation
Tom Bilyeu
A real person whose accident, where a rod shot through his brain and altered his personality, is used as an argument against free will, suggesting behavior is determined by biology and physics.

Free Will Is A Biological Illusion — The Experiment That Proved It Changed How I See Everything
Tom Bilyeu
A railroad foreman whose frontal lobe was impaled by an iron rod in 1848, leading to significant personality changes that suggested a link between brain damage and behavior.