Chloroquine
An antimalarial drug and lysosomal inhibitor that was initially thought to inhibit autophagy in cancer treatment, but its mechanism is broader than just autophagy inhibition.
Common Themes
Videos Mentioning Chloroquine
E1: US Response to COVID-19 & Impact on Startups, VC & Public Markets with David Friedberg
All-In Podcast
An inexpensive drug showing some prophylactic effectiveness against COVID-19 in data from France, but its broad adoption is hindered by lack of clinical trials and FDA approval.
#30 – Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease?
Peter Attia MD
Used in an Egyptian patient's metabolic therapy along with EGCG.
A Conversation with Jonathan Haidt (Episode #204)
Sam Harris
Mentioned in the context of misinformation, where Fox News falsely claimed it was good.
Early Thoughts On a Pandemic: A Conversation with Amesh Adalja (Episode #191)
Sam Harris
A malaria drug being repurposed, showing potential antiviral effects in vitro, and available for off-label prescription.
CORONAVIRUS (COVID-19) - The Basics
Ali Abdaal
An anti-malarial drug that some Chinese doctors are hopeful could be effective against COVID-19, and is particularly valuable for low-income countries due to its low cost.
Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation
FoundMyFitness
An antimalarial drug and lysosomal inhibitor that was initially thought to inhibit autophagy in cancer treatment, but its mechanism is broader than just autophagy inhibition.