Sickle Cell Anemia
A genetic blood disorder caused by a single point mutation leading to misshapen red blood cells, addressed by CRISPR-based therapies in clinical trials.
Videos Mentioning Sickle Cell Anemia

Insights from Dr. Matthew Walker, Adam Grant/Atul Gawande, Diana Chapman, & Rich Roll/David Goggins
Tim Ferriss
A genetic blood disorder mentioned by David Goggins as a condition he has, which makes endurance activities particularly challenging.

#70–David Sinclair, PhD: How cellular reprogramming could slow our aging clock, & the latest on NAD
Peter Attia MD
A genetic disease often considered a poster child for gene therapy due to its single known gene mutation.

323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, & more
Peter Attia MD
A genetic blood disorder caused by a single point mutation leading to misshapen red blood cells, addressed by CRISPR-based therapies in clinical trials.

244 ‒ The history of the cell, cell therapy, gene therapy, and more | Siddhartha Mukherjee
Peter Attia MD
An ancient genetic disease caused by a single amino acid mutation, leading to sickled red blood cells, clogging, and micro-strokes. Discussed as a target for multiple promising gene therapy approaches.

Genetic Screening of Embryos: Risks and Benefits
Sabine Hossenfelder
A monogenic disease tested for using PGT-M, caused by a single gene defect.