Oxytocin

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The 'love neurotransmitter' and safety neurotransmitter. Its receptors can be methylated by cortisol due to stress, impairing feelings of safety and bonding.

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An evolutionarily conserved neuropeptide important for parturition, milk production, and social bonding, sometimes referred to as the 'love neuropeptide'.

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A neurohormone associated with pair bonding and social connection, profoundly increased by MDMA, but not directly responsible for MDMA's pro-social effects.

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A hormone often associated with bonding, mentioned in the context of dog-human attachment and the 'oxytocin thing' for child rearing.

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A neurochemical mentioned as being involved, along with serotonin, in consummatory behaviors and enjoyment within peripersonal space.

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Andrew Huberman

A hormone and neuropeptide involved in social bonds of all kinds, including parent-child attachment, pair bonding, honesty, and sexual response.

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A neuropeptide associated with pair bonding and general bonding, released in massive amounts by MDMA, contributing to feelings of close resonance and association during MDMA-assisted psychotherapy.

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Mentioned as a neuropeptide-like peptide that controls reproduction in various species, similar to tachykinin's evolutionary conservation.

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Andrew Huberman

A hormone, often called the 'love hormone,' that in general, when increased, leads to higher serotonin levels.

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A hormone and peptide involved in milk letdown, pair bonding, and social attachments, with higher receptor levels in the nucleus accumbens potentially linked to more intense yearning in grief.

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A hormone involved in social bonding and released in response to L. reuteri in mouse models, demonstrating a mechanistic link for social behavior improvements.

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A chemical associated with warmth and connection, typically found in more stable, long-lasting relationships, distinct from dopamine's role in infatuation.

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A hormone enhanced during romantic love, playing a role in bonding and social connections.

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A hormone of love and nursing mothers, heavily released by MDMA, which stimulates new neural connections in pro-social brain areas.

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Andrew Huberman

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Benefits & Risks of Peptide Therapeutics for Physical & Mental Health

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A neuropeptide hormone involved in social bonding, socialization, and other functions.

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A hormone involved in the pro-social component of MDMA, with MDMA restoring oxytocin metaplasticity in the nucleus accumbens.

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Often referred to as the 'love hormone,' its role in social connection is discussed in the context of true social interactions versus transient online engagement.

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A hormone mentioned by Thierry Hertoghe as needing to be balanced with testosterone.