Adenosine Receptors
Concept
Receptors in the brain that caffeine acts upon; their internalization due to increased caffeine intake leads to caffeine tolerance.
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Videos Mentioning Adenosine Receptors

Matt Walker: Sleep | Lex Fridman Podcast #210
Lex Fridman
Receptors in the brain that caffeine acts upon; their internalization due to increased caffeine intake leads to caffeine tolerance.

AMA #8: Balancing Caffeine, Decision Fatigue & Social Isolation
Andrew Huberman
Receptors in the brain and body that caffeine blocks. Adenosine buildup signals sleepiness.