Tricyclic Antidepressants (TCAs)

Supplement

Older antidepressants (like desipramine, nortriptyline, amitriptyline) that are effective for pain management by modulating serotonin and norepinephrine and acting as sodium channel blockers, often used for their pain-relieving properties rather than mood.

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Videos Mentioning Tricyclic Antidepressants (TCAs)

345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery

345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery

Peter Attia MD

Older antidepressants (like desipramine, nortriptyline, amitriptyline) that are effective for pain management by modulating serotonin and norepinephrine and acting as sodium channel blockers, often used for their pain-relieving properties rather than mood.