Torcetrapib
Drug / Medication
Pfizer's CETP inhibitor that failed due to off-target effects, increasing blood pressure and aldosterone, leading to higher mortality.
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Videos Mentioning Torcetrapib
255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia
Peter Attia MD
Pfizer's CETP inhibitor that failed due to off-target effects, increasing blood pressure and aldosterone, leading to higher mortality.
407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early, APOE4, and more
Peter Attia MD
An early CETP inhibitor developed by Pfizer, which was stopped due to increased mortality from off-target effects, specifically increased aldosterone and steroid production.