PCSK9

George Church, PhD: Rewriting Genomes to Eradicate Disease and Aging

FoundMyFitness

A gene target in base editing trials for hypercholesterolemia. Humans with natural null mutations for PCSK9 are healthy, indicating its safety and effectiveness as a therapeutic target.

The impact of body fat on metabolic health | Peter Attia & Ethan Weiss

Peter Attia MD