Metformin
Named as one of the drugs under study or use in longevity research to mimic calorie-restriction effects.
Research
Common Themes
Videos Mentioning Metformin

#500! KevKev TimTim TalkTalk on Dragon Slaying, Lessons Learned, Viagra, and Assorted Nonsense
Tim Ferriss
A drug sometimes considered for longevity, which Tim Ferriss does not currently take but might consider in the future.

Intermittent Fasting to Improve Health, Cognition & Longevity | Dr. Satchin Panda
Andrew Huberman
A drug that activates 'AMP kinase,' mimicking a fasting state and potentially increasing longevity.

Dr. Arthur De Vany Interview | The Tim Ferriss Show (Podcast)
Tim Ferriss
A drug sometimes discussed in relation to mTOR and lifespan extension.

Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer
Tim Ferriss
A drug used by type 2 diabetics to decrease hepatic gluconeogenesis and is being researched for cancer prevention and treatment due to its activation of AMPK and calorie restriction mimicking effects.

Dr David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!
The Diary Of A CEO
A drug that has been shown to interfere with muscle growth in weightlifters by affecting mitochondria; Dr. Sinclair suggests pulsing it for longevity benefits.

Bryan Johnson: I Just Took the Most Powerful Dose of DMT in the World... Here's What It Was Like
All-In Podcast
A drug commonly used for managing blood glucose levels, mentioned in the context of longevity interventions. It is contrasted with the metabolic reset observed from psilocybin.