Key Moments
Cell Swelling, Genetic Ceilings, Touch-and-Go Deadlifts, and Load-Specific Adaptations (Episode 34)
Key Moments
Podcast covers feats of strength, genetic limits, deadlift technique, nutrition, and sourdough baking.
Key Insights
The concept of a strict 'genetic ceiling' for muscle growth, like a Fat-Free Mass Index (FFMI) of 25, is often overstated, with many individuals naturally capable of exceeding this.
Touch-and-go deadlifts are generally safe and potentially beneficial for hypertrophy compared to bouncing, provided a controlled eccentric phase.
Diet breaks are primarily beneficial for fat loss by mitigating metabolic adaptation, and their physiological benefit during bulking is questionable.
Maintaining muscle mass and strength without significant hypertrophy can be achieved by focusing on high-intensity, low-volume training and staying further from failure.
Pre- and post-workout nutrition, focusing on digestible protein and carbohydrate sources, is important for performance and recovery, though the 'anabolic window' is wider than often assumed.
The 'acid-ash hypothesis' linking high protein intake to bone loss is not supported by current research; high protein diets may even be beneficial for bone density during weight loss.
FEATS OF STRENGTH AND RESEARCH RESOURCES
The episode begins by highlighting numerous recent feats of strength, including Julius Maddox becoming the first person to bench over 750 pounds and impressive deadlifts from Yury Belkin and Dmitriy Klokov. It also introduces a new resource: the Stronger By Science 'Studies Archive' on their website, which curates monthly research findings to help listeners stay updated on scientific literature relevant to strength and physique athletes.
DEBUNKING GENETIC LIMITS AND DEADLIFT TECHNIQUES
The discussion addresses listener questions about the Fat-Free Mass Index (FFMI) and genetic potential for muscle growth. Contrary to popular belief, an FFMI of 25 is not an insurmountable natural limit, with studies showing significant percentages of athletes in various sports exceeding this. The podcast also clarifies deadlift technique, advising against 'bouncing' reps due to injury risk, while endorsing controlled 'touch-and-go' reps for their potential to improve hypertrophy by ensuring a proper eccentric phase.
NUTRITION STRATEGIES FOR BULKING AND MUSCLE MAINTENANCE
Nutritional advice is provided for both bulking and muscle maintenance without further hypertrophy. Diet breaks are discussed as effective for cutting by managing leptin levels and metabolic adaptation, but are deemed less physiologically beneficial during bulking, where enjoyment and energy density adjustments are more crucial. For those aiming to maintain muscle and strength without gaining size, strategies include reducing training volume, increasing intensity with lower reps, training further from failure, and potentially using ice baths.
PRE- AND POST-WORKOUT NUTRITION CONSIDERATIONS
The importance of pre-workout nutrition is emphasized, particularly for early morning training. Digestible protein and carbohydrate sources are recommended to fuel workouts and prevent hunger. While the 'anabolic window' is now understood to be wider than previously thought, consuming protein within one to two hours post-workout is still advised for optimal recovery and muscle protein synthesis. The focus is on providing adequate nutrients without causing digestive distress.
RESEARCH ROUNDUP: PROTEIN, BONE HEALTH, AND MUSCLE FLUID
This segment delves into recent research findings. A meta-analysis suggests high-protein diets may attenuate bone density loss during weight loss, debunking the 'acid-ash hypothesis'. Another study explores the link between intramuscular fluid volume and passive muscle tension using animal models and a novel physical model, suggesting fluid increases could impact muscle mechanics. While speculative for human application, it sparks discussion on potential implications for fatigue and performance during intense training or dieting.
LOAD-SPECIFIC ADAPTATIONS AND DEBATES IN TRAINING
The conversation shifts to research on resistance exercise, specifically high-load vs. low-load training. While both methods yield similar overall muscle hypertrophy, nuanced differences in mitochondrial adaptations and fiber-type specific growth are discussed. The prevailing view is that significant load-dependent fiber-type hypertrophy is not a major concern for most individuals, as both heavy and lighter training generally stimulate growth in both Type I and Type II fibers.
THE RED MEAT AND PROCESSED MEAT DEBATE: A DRAMA UPDATE
A significant portion of the podcast is dedicated to the controversy surrounding guidelines on red and processed meat consumption. It details the backlash against research that challenged previous strong recommendations against these foods, including allegations of 'information terrorism' and attempts to have the papers retracted. The segment highlights concerns about conflicts of interest, the integrity of the scientific process, and includes an open letter from the Chancellor of Texas A&M to the President of Harvard regarding the matter.
MASTERING SOURDOUGH BREAD MAKING
The podcast concludes with practical advice on making sourdough bread at home. Greg shares his experiences and tips for creating a healthy sourdough starter using kefir or yogurt and a small amount of commercial yeast. He emphasizes the importance of long fermentation times for authentic sour flavor development, suggesting a process that can take 10-18 hours, and encourages listeners to experiment to find what works best for their specific conditions and ingredients.
Mentioned in This Episode
●Supplements
●Products
●Software & Apps
●Companies
●Organizations
●Books
●Studies Cited
●People Referenced
Sourdough Starter Success Tips
Practical takeaways from this episode
Do This
Avoid This
Common Questions
Greg now publishes his monthly list of relevant studies, along with archives, on strongerbyscience.com/studies-archive. The website also features a database of podcast Q&As and a list of systematic reviews and meta-analyses relevant to strength and physique athletes.
Topics
Mentioned in this video
Powerlifter mentioned as the second-best deadlifter in the 82.5 kg class behind Dmitry Nasonov and also broke the all-time world record total at 90 kg (198 lbs) in his first competition in that weight class.
Holds the current world record deadlift of 298 kg in the 66 kg (145 lbs) weight class.
Powerlifter competing in the 59 kg (130 lbs) class; demonstrated a 290 kg (693 lbs) deadlift for a double with straps, indicating immense pulling strength despite small hands and grip limitations.
Recently set the untested deadlift record of 303 kg in the 66 kg weight class a couple of months prior to the podcast.
Holds the deadlift record of 286 kg in the 60 kg class for non-IPF federations.
Previously associated with the True Health Initiative, he also cut ties, sharing Stefan Gihona's disappointment and concern for scientific integrity.
Researcher from Harvard School of Public Health and member of the True Health Initiative's council of directors, whose funding sources were questioned in light of the red meat controversy.
Mentioned as arguably the 'goat of powerlifting,' having won 15 straight IPF World Championships.
Author of the JAMA blog post detailing the backlash and alleged ethical violations surrounding the red meat research controversy.
Researcher from Harvard School of Public Health and member of the True Health Initiative's council of directors, whose funding sources were questioned in light of the red meat controversy.
Powerlifter who became the first human to bench over 750 pounds (755 lbs). Known for his extremely strong and decisive lifts.
Female single-ply lifter who benched 225 kg (496 lbs), surpassing her own world record and approaching the 500-pound barrier in the 84 kg class.
Lifter from the 82.5 kg (181 lbs) class who holds the world record for deadlift at 400 kg (881 lbs), considered one of the most impressive records.
Legendary powerlifter whose old deadlift records (859 lbs at 198 lbs, 903 lbs at 220 lbs) are used as benchmarks for comparison.
Russian powerlifting coach whose Instagram account highlighted the rise of powerlifting in China and Mihai as a promising lifter.
Holds the current raw deadlift record of 277.5 kg in the 59 kg weight class.
Considered the 'god of the lightweight deadlift,' holding the single-ply record of 310 kg in the 60 kg class; used as a benchmark for Sergey Fedosienko's impressive lift.
Swedish discus thrower, reigning world champion, who deadlifted 350 kg (771 lbs) for 5 reps; noted for his raw strength despite imperfect sumo deadlift technique.
Powerlifter who recently squatted 462 lbs at 125 lbs bodyweight, and later 444 lbs for 3 reps, demonstrating incredible strength.
17-year-old powerlifter who squatted 832 lbs convincingly deep in a meet and totaled 1856 lbs, setting junior records and showing immense potential.
Content creator who made a video showing his DEXA scan results with an FFMI of 24.6, suggesting it was close to a human limit, a claim which Greg and Eric dispute.
Co-host of Stronger By Science, mentioned when asked about his FFMI. Also referenced for his review of a short-term carb load study in bodybuilders.
Humorously compared to the hosts' (non-journalistic) approach to discussing controversies, highlighting the entertainment aspect.
Mr. America winner who dominated so thoroughly that rules were changed to prevent single competitors from cannibalizing the competition.
Founder of True Health Initiative and a prominent figure advocating for plant-based diets, heavily criticized for alleged attempts to suppress research and for his shifting stance on industry funding.
Strength athlete who, when discussed with Eric and Greg, inspired the phrase 'keep turning over more rocks' in the pursuit of gains.
Researcher whose lab published a high-quality paper comparing high-load and low-load training, finding similar type 1 and type 2 fiber hypertrophy.
Researcher who cut ties with the True Health Initiative after reading the JAMA blog post, emphasizing the importance of scientific integrity over opinions on red meat.
Mentioned as an osmolytic supplement that can increase fluid volume within the muscle, potentially relevant to muscle performance.
Recommended as a sufficient protein source for pre-workout shakes, with typical dosage being 20-40 grams, depending on individual tolerance and size.
Recommended as a quick-digesting carbohydrate source for pre-workout, with a suggested dosage of 20-60 grams depending on body size and training volume.
Mentioned as an osmolytic supplement that can increase fluid volume within the muscle, potentially relevant to muscle performance.
Greg produces a monthly journal sweep for Mass, a publication related to strength and fitness research.
Eric Trexler took a class on meta-analyses at UNC with Charlie Poole.
Charlie Poole, who taught Eric Trexler's meta-analysis class, is a significant figure in the Cochrane Collaboration.
A funding mechanism associated with Texas A&M University, which received a very small portion of its funding (1.5%) from the beef industry, becoming a focal point in the conflict of interest allegations.
A non-profit founded by David Katz, heavily criticized for allegedly orchestrating a campaign to suppress research on red and processed meat and for violating embargo policies.
Federal entity providing about half of AgriLife's funding, contrasting with the minor beef industry funding.
Its Chancellor sent an open letter to the President of Harvard, calling for an investigation into allegations against Harvard faculty members (Willett and Hu) for mischaracterizing scientific research.
Humorously thanked as a sponsor for funding the discussion on the red meat controversy, playing on the 'big beef industry' allegations.
The journal that published controversial papers on red and processed meat, and whose blog post revealed the backlash and alleged misconduct by lobbying groups.
Greg exceeded Gmail's daily free email limit when sending out study lists, prompting a change in how he shares research updates.
Greg considered using MailChimp for his research study emails but found it too expensive for the number of subscribers.
The website where Greg now publishes his monthly research studies archive and other free resources like a Q&A database and meta-analysis list.
Recommended as an ingredient for sourdough starter to introduce lactic acid bacteria and establish the correct pH quickly, especially unpasteurized varieties.
Recommended as an alternative to kefir for sourdough starter, mixed with water, to provide lactic acid bacteria and regulate pH.
Used in a physical model in the Sloboda et al. study to represent a water-filled bladder within a plastic fiber structure mimicking the extracellular matrix of muscle.
Can be used in small amounts (1/8 to 1/4 teaspoon) to kickstart a sourdough starter by providing a quick initial yeast population that is later outcompeted by wild yeast.
A study that found muscle fiber swelling could depress force production by 10-15% when fibers were swollen to 116% of their original diameter.
The study often cited for the FFMI limit of 25, which, upon re-examination, does not support a strict limit for shredded individuals, as its sample included people up to 17% body fat.
Study titled 'Passive muscle tension increases in proportion to intramuscular fluid volume' which explored the correlation between muscle fluid volume and passive muscle tension using bullfrog muscle and a physical model.
The institution where researchers Walter Willett and Frank Hu are faculty members, whose president was called upon by the Chancellor of Texas A&M to investigate their alleged mischaracterization of science.
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