Ketamine
A legal substance used in therapy, intriguing due to its similar effects to psilocybin and MDMA despite being chemically different.
Research
Common Themes
Videos Mentioning Ketamine

Dr. Adam Gazzaley - Brain Optimization and The Future of Psychedelic Medicine | The Tim Ferriss Show
Tim Ferriss
A dissociative anesthetic that can induce deep psychedelic experiences at sufficient doses, discussed by Tim Ferriss from personal experience during a five-session series of intravenous infusions.

#25 – Scott Harrison: transformation, finding meaning, and taking on the global water crisis
Peter Attia MD
An illicit drug Scott Harrison used during his nightlife promotion years.

Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson
Andrew Huberman
An NMDA antagonist psychedelic known to induce dissociative and insightful experiences, used therapeutically and recreationally, with different effects based on dosage.

Understand and Use Dreams to Learn and Forget | Huberman Lab Essentials
Andrew Huberman
A dissociative anesthetic used in clinical settings for trauma treatment, believed to block plasticity and prevent the connection between intense emotions and experiences.

A Masterclass in Riding the Waves of Life — “The School for Good and Evil” Creator Soman Chainani
Tim Ferriss
A dissociative anesthetic used in a clinical setting for mental health treatment, which Soman Chainani experienced as life-changing for his anxiety and emotional numbness.

Understanding & Conquering Depression
Andrew Huberman
A dissociative anesthetic and formerly a drug of abuse, now being explored in psychiatric clinics as a promising treatment for major depression by inducing neuroplasticity and dissociative states.

Joscha Bach: Nature of Reality, Dreams, and Consciousness | Lex Fridman Podcast #212
Lex Fridman
Mentioned as a substance that can be dangerous in larger doses due to its potential to depress breathing.

Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams
Andrew Huberman
A drug increasingly used to treat depression, with effects that may not arise from its dissociative properties, and a focus of research in Dr. Williams's lab.

How to Improve at Learning Using Neuroscience & AI | Dr. Terry Sejnowski
Andrew Huberman
A drug known as a party drug and anesthetic, which can induce temporary psychosis similar to schizophrenia by binding to NMDA receptors and reducing inhibitory circuit strength.

Jessica Lahey on Parenting, Desirable Difficulties, And Much More! | The Tim Ferriss Show
Tim Ferriss
A substance mentioned by Tim Ferriss as being seductive for its subtractive purpose, akin to alcohol for anxiety, but with its own applications and risks.

Rick Doblin: Psychedelics | Lex Fridman Podcast #202
Lex Fridman
An anesthetic approved as S-ketamine for depression, used in psychedelic doses (one-tenth the anesthetic dose) to reveal deeper information, noted for varying effects between adults and children.

Understanding & Healing the Mind | Dr. Karl Deisseroth
Andrew Huberman
A dissociative drug that can cause dissociative states, used in studies to understand the circuit basis of dissociation.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Seattle, WA
Andrew Huberman
A substance being studied for its therapeutic potential in mental health treatments, with early-stage research ongoing.

The Science & Treatment of Bipolar Disorder
Andrew Huberman
An FDA-approved treatment for major depression that transiently increases neural circuit excitability, working opposite to lithium on homeostatic plasticity.

The Science & Treatment of Obsessive Compulsive Disorder (OCD)
Andrew Huberman
A legal prescription drug (in the US) that acts on the glutamate system, being explored for trauma, depression, and OCD, showing some promising but not overwhelming results for OCD.

The New Frontiers of Mental Health — Brain Stimulation, Rapid-Acting Tools for Depression, and More
Tim Ferriss
A drug that produces about a 30% spot remission rate with a single infusion for depression, with efficacy increasing with more treatments, though it accumulates more time compared to Saint.

Dr. Stefi Cohen — 25 World Records, Power Training, and More | The Tim Ferriss Show
Tim Ferriss
A substance used by Tim Ferriss in infusions, which unexpectedly alleviated his chronic mid-back pain by potentially providing a 'hard reset' for pain pathways.

Therapy, Treating Trauma & Other Life Challenges | Dr. Paul Conti
Andrew Huberman
Mentioned as a distinct category of medicine from true psychedelics, with laboratories at Stanford working on it.

The Random Show — New Year's Resolutions, 2010-2019 Lessons Learned, Finding Joy, and Much More
Tim Ferriss
A novel treatment procedure for psychiatric conditions, recognized for its interesting effects but also its challenges.

The Random Show — Blockchain/Crypto Investing, NFT Experiments, Dogecoin, Zen Buddhism, and More
Tim Ferriss
A drug that can cause nausea at higher doses, often administered with Zofran in a clinical setting.

Marcela Ot’alora — How to Become a Psychedelic Therapist | The Tim Ferriss Show
Tim Ferriss
A substance mentioned as another legal way to create non-ordinary states of consciousness, which can be useful for therapist training.

The Science of Emotions & Relationships
Andrew Huberman
A dissociative anesthetic used for PTSD treatment and recreationally, mentioned in the context of a marketed nasal spray combining it with oxytocin, which Huberman finds puzzling and potentially dangerous.

The Random Show with Tim Ferriss & Kevin Rose — Affordable Luxuries, Brain Stimulation, and More!
Tim Ferriss
An anesthetic drug, jokingly referenced by Tim Ferriss in the context of 'ketamine suppositories' and unusual drug consumption methods.

243 ‒ The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito
Peter Attia MD
A drug that, like cocaine, is now being found to be laced with fentanyl, even when legally prescribed.