Key Moments

#126–Matthew Walker, Ph.D.: Sleep & immune function, chronotypes, hygiene tips, & his book

Peter Attia MDPeter Attia MD
People & Blogs4 min read102 min video
Aug 31, 2020|19,190 views|444|25
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TL;DR

Matthew Walker discusses COVID-19's impact on sleep, dreaming, chronotypes, sleep hygiene, and book corrections with Peter Attia.

Key Insights

1

COVID-19 pandemic has led to increased sleep duration and reduced social jet lag for many, though sleep quality perception varies.

2

Dreaming may increase due to extended REM sleep periods in the latter half of the night, and as a mechanism for processing emotional distress.

3

Alcohol negatively impacts sleep quality, particularly REM sleep, potentially creating a cycle of increased anxiety and further alcohol consumption.

4

Specific sleep hygiene practices, such as maintaining a wind-down routine, removing clocks, and limiting technology use, are crucial for better sleep.

5

Understanding chronotypes (morning/evening preference) is genetically determined and influences optimal sleep-wake schedules, with societal structures often clashing with individual chronotypes.

6

Sleep significantly impacts immune function, with insufficient sleep increasing susceptibility to infection and reducing vaccine efficacy.

7

Matthew Walker addresses and corrects 13 identified errors and clarifies interpretations in his book 'Why We Sleep', with a second edition forthcoming.

COVID-19'S IMPACT ON SLEEP PATTERNS

The COVID-19 pandemic has notably affected sleep patterns. Data suggests an increase in total sleep time for many individuals, potentially due to reduced work commute times and social obligations. This shift has also led to a decrease in social jet lag—the discrepancy between weekday and weekend sleep schedules. However, some individuals report a decrease in sleep quality, possibly linked to heightened anxiety and stress related to the pandemic's uncertainties, job security, and general life disruptions experienced during lockdowns.

THE SCIENCE AND FUNCTION OF DREAMING

Dreaming, primarily associated with REM sleep, serves crucial emotional functions. REM sleep acts as 'overnight therapy,' helping to process challenging emotional experiences and reduce their intensity. When individuals experience heightened stress or trauma, sleep, particularly REM sleep, responds by providing more dream-time to help 'soothe' these difficult emotions. This mechanism is vital for emotional convalescence, suggesting that time spent in REM sleep is key to healing emotional wounds.

ALCOHOL'S DETRIMENTAL EFFECT ON SLEEP QUALITY

Alcohol, while acting as a sedative that might hasten sleep onset, significantly degrades sleep quality. It disrupts the natural sleep cycle, leading to more fragmented sleep and increased awakenings. Alcohol suppresses REM sleep, particularly in the latter half of the night, and can stimulate the sympathetic nervous system, releasing wake-promoting chemicals. This reduction in REM sleep impairs the body's ability to process emotions, potentially exacerbating anxiety and creating a cycle where individuals reach for alcohol to cope, further compromising sleep.

OPTIMIZING SLEEP THROUGH HYGIENE AND ROUTINES

Effective sleep hygiene involves several key practices. Maintaining consistent sleep and wake times, ensuring sufficient darkness at night, and obtaining adequate daylight exposure, especially in the morning, are foundational. Establishing a relaxing wind-down routine for 30-60 minutes before bed is crucial to signal the body it's time to sleep. Additionally, removing clocks from the bedroom to avoid anxiety about lost sleep time, keeping technology out of the bedroom, and adopting an 'out of bed if awake for more than 20 minutes' rule helps prevent associating the bed with wakefulness.

UNDERSTANDING AND HARMONIZING WITH CHRONOTYPES

Chronotypes, or one's natural inclination towards being a morning or evening person, are strongly influenced by genetics. While 25-30% of the population are morning types and a similar percentage are evening types, the rest fall in between. These chronotypes shift throughout life, notably during adolescence when eveningness increases, often clashing with early school start times. Recognizing one's chronotype, often assessed via the Morningness-Eveningness Questionnaire (MEQ), is vital for aligning daily schedules with biological rhythms to improve well-being and avoid the negative consequences of fighting one's natural sleep-wake pattern.

SLEEP'S CRITICAL ROLE IN IMMUNE FUNCTION

Sleep is intrinsically linked to immune health. Studies show that individuals sleeping less than seven hours are significantly more likely to contract infections like the common cold. Insufficient sleep also increases the risk of conditions like pneumonia and critically impacts adaptive immunity; sleep deprivation before vaccination can reduce antibody response by over 50%, rendering vaccines less effective. While direct data on sleep's impact on COVID-19 vulnerability is still emerging, the strong association between sleep and immune function highlights its importance for fighting off pathogens and ensuring vaccine efficacy.

ADDRESSING ERRORS AND INTERPRETATIONS IN 'WHY WE SLEEP'

Matthew Walker acknowledges that 13 factual errors have been identified and corrected in the first edition of 'Why We Sleep,' with a second edition now in production. These corrections range from specific data points, such as the exact number of participants in cited studies, to the classification of risks, like short sleep's association with specific cancers rather than all cancers. Interpretive errors, such as the relationship between long sleep and mortality (initially attributed to underlying illness, now also considering poor sleep quality), have also been addressed and clarified in extensive detail on his blog and will be updated in the new edition.

Essential Sleep Hygiene & Optimization Tips

Practical takeaways from this episode

Do This

Maintain regularity: go to bed and wake up at the same time daily, even on weekends.
Ensure sufficient darkness at night and ample daylight exposure in the first half of the day.
Keep your bedroom cool, as a lower body temperature facilitates sleep.
Leave your bed if you can't fall asleep within 20 minutes; return only when sleepy.
Establish a consistent 'wind down' routine (15-30 mins) before bed, including light stretches or meditation.
If using your phone in the bedroom, use it while standing up to encourage putting it away when you want to lie down.
Delay checking your phone for at least an hour after waking up to avoid anticipatory anxiety.

Avoid This

Avoid naps during the day if you struggle with falling or staying asleep at night.
Keep digital clock faces in your bedroom, as knowing the time can increase sleep-related anxiety.
Bring technology (phones, gadgets) into the bedroom or make it the first thing you check in the morning.
Consume alcohol or caffeine in the afternoon or evening, as they disrupt sleep architecture.

Common Questions

Studies from sleep tracking companies and peer-reviewed journals suggest that total sleep time increased by about 15-20 minutes on average. Social jet lag, the difference in sleep timing between weekdays and weekends, also decreased for many, allowing people to sleep more in harmony with their natural chronotype.

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