Caffeine

Boost Attention & Memory with Science-Based Tools | Dr. Wendy Suzuki

Andrew Huberman

A stimulant, where its abuse is noted among students, though Dr. Huberman personally uses it.

Doping, Collagen, Goals, and Hyperplasia (Episode 33)

Stronger By Science

A stimulant discussed for its potential to improve alertness and cognitive function, especially when combined with theanine and tyrosine.

How Our Hormones Control Our Hunger, Eating & Satiety

Andrew Huberman

A stimulant that reliably increases blood glucose levels slightly. Also acts as a diuretic, potentially affecting electrolyte balance.

The Science of Emotions & Relationships

Andrew Huberman

Mentioned as potentially increasing oxytocin release at low doses, but Huberman notes the evidence for this effect is not strong.

Q&A: Bands, Chains, Useful Supplements, and Tweaking Your Program (Episode 27)

Stronger By Science

A performance-enhancing supplement, especially reliable for endurance and lifting performance, often used in conjunction with tyrosine and theanine.

Psychedelics — Microdosing, Mind Enhancing Methods, and More | The Tim Ferriss Show (Podcast)

Tim Ferriss

A common stimulant with a differing safety profile compared to psychedelics.

Using Science to Optimize Sleep, Learning & Metabolism

Andrew Huberman

A stimulant often included in nootropics, which can increase focus up to a certain point by impacting adenosine pathways.

Master Your Sleep & Be More Alert When Awake

Andrew Huberman

A substance that acts as an adenosine antagonist, blocking sleepiness signals and increasing dopamine. Its tolerance varies greatly among individuals.

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)

Tim Ferriss

A compound found in black coffee that can produce metabolic effects and influence peripheral oscillators, often considered by strict time-restricted eating definitions to break a fast.

The Biology of Breast Milk

FoundMyFitness

Using Science to Optimize Sleep, Learning & Metabolism | Huberman Lab Essentials

Andrew Huberman

A stimulant often found in nootropics, used for alertness.

Q&A: Cortisol, Hydration, Anti-Nutrients, and Deadlift Recovery (Episode 50)

Stronger By Science

A stimulant with ergogenic effects that can increase strength and power, helps with focus and perceived effort, and has a longer half-life than nicotine.

257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies

Peter Attia MD

A stimulant whose timing and dose were tinkered with to optimize driver reaction time off the start line in F1.

Tools for Nutrition & Fitness | Dr. Layne Norton

Andrew Huberman

Discussed as an example of looking at the overall outcome rather than isolated biochemical pathways. While it inhibits glycogen phosphorylase, its overall effect is sympathetic nervous system activation and fuel liberation, not glycogen synthesis.

Immune Function, Home-Based Workouts, Fat Burners, and Lifting with Long Limbs (Episode 38)

Stronger By Science

Can have modest effects on energy expenditure and appetite control, but the effects are not significant enough to be a primary fat loss strategy.

Q&A: Carbs, Sodium, and Experimenting with Your Training (Episode 23)

Stronger By Science

A pre-workout stimulant that can provide a boost, typically dosed 30-60 minutes before training.

Red Meat, Deloads, and Pain with Dr. Michael Ray (Episode 22)

Stronger By Science

A well-supported supplement for performance, which Dr. Rae consumes, confirming its efficacy is backed by research.

Sex Differences in Fatigue and Recovery, and Dr. Jason Cholewa (Podcast Episode 2)

Stronger By Science

A common ergogenic ingredient in pre-workouts, often present in high doses, and whose effects are often attributed to the entire pre-workout formula.

205 - Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)

Peter Attia MD

An ingredient often found in pre-workouts that, when combined with creatine, can cause GI discomfort for some individuals.

Dom D'Agostino Returns (Full Episode) | The Tim Ferriss Show (Podcast)

Tim Ferriss

A stimulant with extensive research, used by the military for efficacy and safety, known to be an appetite suppressant and antioxidant.

Creatine, Genetics, and Dr. Peter Fitschen (Podcast Episode 1)

Stronger By Science

A stimulant supplement discussed for its interaction with Creatine and genetic variations in metabolism.

AMA #8: Balancing Caffeine, Decision Fatigue & Social Isolation

Andrew Huberman

A commonly consumed drug that blocks adenosine receptors, providing energy and focus but can disrupt sleep and cause anxiety if overused or taken too close to bedtime.

Dr. Andy Galpin: Optimal Nutrition & Supplementation for Fitness | Huberman Lab Guest Series

Andrew Huberman

A stimulant with ergogenic effects, particularly for endurance performance. Dosage of 1-3mg/kg body weight, taken 30 minutes prior to exercise, is recommended. Higher doses (above 5mg/kg) can degrade performance. It acts as an adenosine antagonist, borrowing against the adenosine system with interest. Widely available in coffee, tea, pre-workout.

Dr. Dominic D'Agostino on Fasting, Ketosis, and The End of Cancer

Tim Ferriss

A stimulant present in Utopian (cognitive enhancement agent), providing about 100 milligrams per serving.