TAME trial
A clinical trial using metformin to delay the onset of a second age-related disease in people who already have one, representing a strategy for aging intervention trials.
Videos Mentioning TAME trial

175 - The biology of aging, rapamycin, and other interventions that target the aging process
Peter Attia MD
A clinical trial using metformin to delay the onset of a second age-related disease in people who already have one, representing a strategy for aging intervention trials.

Journal Club with Dr. Peter Attia | Metformin for Longevity & The Power of Belief Effects
Andrew Huberman
A clinical trial designed to prospectively and through random assignment investigate if Metformin provides a geroprotective benefit to non-diabetics.

The Life-Extension Episode With Dr. Matt Kaeberlein | The Tim Ferriss Show
Tim Ferriss
A human clinical trial examining Metformin's effects on age-related diseases, which has gained FDA agreement to consider a collection of age-related diseases as one endpoint.

#35 – Nir Barzilai, M.D.: How to tame aging
Peter Attia MD
Targeting Aging with Metformin, a prospective clinical trial led by Dr. Barzilai to test Metformin's effect on aging in non-diabetics, seeking FDA approval for aging as an indication.

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock
Peter Attia MD
A proposed clinical trial investigating metformin for healthy aging in humans, discussed for its potential to build scientific and public credibility for aging research.