psilocybin
Psychedelic compound discussed in the context of MRI studies; relates to the psilocybin/psilocin administration in subjects.
Research
Common Themes
Videos Mentioning psilocybin

Stuart Hameroff - What do Theories of Consciousness Mean?
Closer To Truth
Psychedelic compound discussed in the context of MRI studies; relates to the psilocybin/psilocin administration in subjects.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Chicago, IL
Andrew Huberman
The psychoactive compound found in 'magic mushrooms,' discussed for its potential in treating depression and stimulating serotonin receptors, with research showing promise but also caution advised.

190 - How to heal from trauma and break the cycle of shame
Peter Attia MD
One of two substances discussed as a 'shining hope for the future' in trauma therapy, moving towards clinical approval for its potential to foster understanding and change.

LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Toronto, ON
Andrew Huberman
Discussed in the context of increasing neuroplasticity, with macro-dosing showing promise for depression and eating disorders, but not microdosing.

182 - Psychedelics & Recreational Drugs
Peter Attia MD
The active ingredient in magic mushrooms, historically used in many cultures. It was initially banned in 1971 but the mushrooms themselves only became illegal in the UK in 2005 due to commercial sales triggering political and media outrage. Currently being researched for depression.

All Things Sleep (Weight Gain, Alzheimer’s Disease, Caffeine, and More) — Dr. Matthew Walker
Tim Ferriss
A psychoactive compound from mushrooms, discussed for its potential to alter sleep needs and dream experiences, with reported vivid dreams when taken pre-sleep.

Mental Health Toolkit: Tools to Bolster Your Mood & Mental Health
Andrew Huberman
A compound closely mimicking serotonin, being explored in clinical trials at relatively high dosages to access neuroplasticity for major depression treatment.

Calm App Founder: From $0 To $2 Billion By Making The World Meditate: Michael Acton Smith | E117
The Diary Of A CEO
A psychedelic compound being researched for its potential to help alleviate mental health issues when combined with therapy.

Johann Hari: Everything You Think You Know About Meaning & Happiness Is Wrong | E82
The Diary Of A CEO
The active compound found in magic mushrooms, being researched for its effectiveness in treating treatment-resistant depression by providing profound spiritual and connected experiences.

#135 - BJ Miller, M.D.: How understanding death leads to a better life
Peter Attia MD
A psychedelic substance being researched for its significant positive impact on end-of-life anxieties, fear of death, and feelings of meaninglessness in terminally ill patients.

Jack Kornfield — How to Overcome Apathy and Find Beautiful Purpose
Tim Ferriss
Mentioned as a psychedelic compound with promising therapeutic uses, particularly in group therapy settings for treatment-resistant depression.

Michael Pollan — This Is Your Mind on Plants | The Tim Ferriss Show
Tim Ferriss
A psychedelic compound, subject of research into its therapeutic benefits, especially for end-of-life distress and depression.

Life, Death & the Neuroscience of Your Unique Experience | Dr. David Linden
Andrew Huberman
A psychedelic compound (still illegal, but decriminalized in places) undergoing clinical trials for depression, showing significant relief in 65-80% of people and is known to encourage neuroplasticity.

Jason Calacanis on Brooklyn Grit, Big Asks, The Magic of Thinking Big, and More
Tim Ferriss
A psychedelic compound being researched for its therapeutic potential in conditions like treatment-resistant depression.

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
A compound that can induce neuroplasticity to relieve major depression, which was covered in a previous podcast episode.

Q&A with Tim — Exercise And Morning Routines, Holotropic Breathwork, and More | The Tim Ferriss Show
Tim Ferriss
A psychoactive compound found in magic mushrooms, studied by Johns Hopkins for treating addiction and existential distress.

Dr. Gina Poe: Use Sleep to Enhance Learning, Memory & Emotional State | Huberman Lab Podcast
Andrew Huberman
A psychedelic substance being clinically studied for trauma treatment.

Carl Hart: Heroin, Cocaine, MDMA, Alcohol & the Role of Drugs in Society | Lex Fridman Podcast #233
Lex Fridman
A psychedelic drug that Hart notes is increasingly viewed more favorably, potentially offering positive experiences when used responsibly.

How Your Brain’s Reward Circuits Drive Your Choices | Dr. Robert Malenka
Andrew Huberman
A classic hallucinogen, similar to LSD, that largely works through activation of the serotonin 2A receptor, leading to mystical subjective effects.

The Best Kept Secret In History?: A Conversation with Brian Muraresku (Episode #346)
Sam Harris
Psychoactive compound found in 'magic mushrooms', proposed as a component of the ancient Eleusinian Mysteries potion.

Kelsi Sheren: War, Artillery, PTSD, and Love | Lex Fridman Podcast #230
Lex Fridman
A psychedelic compound found in mushrooms, mentioned as a substance used for microdosing to treat depression and as part of psychedelic treatments for veterans.

Philip Goff: Consciousness, Panpsychism, and the Philosophy of Mind | Lex Fridman Podcast #261
Lex Fridman
Mentioned as a substance used in rigorous university studies for exploring mystical experiences and gaining wisdom.

The Science of MDMA & Its Therapeutic Uses: Benefits & Risks | Huberman Lab Podcast
Andrew Huberman
A classic psychedelic found in 'magic mushrooms,' primarily activating the serotonin 5HT2A receptor, similar to LSD, and under investigation for depression.

The Possibilities of Mind-Altering Compounds | Dr. Suresh Muthukumaraswamy | The Tim Ferriss Show
Tim Ferriss
A classical psychedelic found in magic mushrooms, primarily acting on the serotonin 2A receptor. Research suggests it can have durable antidepressant effects, possibly linked to addressing root narratives.