Memantine
Drug / Medication
An NMDA receptor blocker used to treat Alzheimer's disease, but noted to have no antidepressant effects, contrasting with ketamine's action.
Mentioned in 2 videos
Videos Mentioning Memantine

Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast
Andrew Huberman
An NMDA receptor blocker used to treat Alzheimer's disease, but noted to have no antidepressant effects, contrasting with ketamine's action.

#38–Francisco Gonzalez-Lima, Ph.D.: Alzheimer’s disease & the vascular hypothesis
Peter Attia MD
A drug approved for moderate to severe Alzheimer's, which prevents excitotoxicity but is considered counterproductive as it rescues functionally incompetent cells.