Alzheimer's disease
A neurodegenerative disease linked to APOE4 and amyloid beta pathology, where Vitamin D supplementation has shown potential benefits in reducing risk and progression.
Common Themes
Videos Mentioning Alzheimer's disease

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?
Peter Attia MD
A neurodegenerative disease that shares commonalities with mitochondrial disorders, potentially stemming from neuronal energy crises.

The Random Show — New Year's Resolutions, 2010-2019 Lessons Learned, Finding Joy, and Much More
Tim Ferriss
A neurodegenerative disease that runs in Tim Ferriss's family, leading to his interest in neuroscience and potential treatments, including psychedelics.

252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting
Peter Attia MD
A neurodegenerative disease that Rhonda has a personal and scientific interest in due to family history and genetic predisposition. Discussed in relation to current understanding and prevention strategies.
![Optimizing brain health: Alzheimer's risk factors, APOE, & prevention strategies [AMA 46 sneak peek]](https://i.ytimg.com/vi/ELK-k7DO1Is/maxresdefault.jpg)
Optimizing brain health: Alzheimer's risk factors, APOE, & prevention strategies [AMA 46 sneak peek]
Peter Attia MD
The primary focus of the AMA, discussing its diagnosis, risk factors, genetic components, and prevention strategies.

#57–Rick Rubin: collaborating with the greatest living musicians, & his personal weight loss story
Peter Attia MD
A neurodegenerative disease that Peter Attia was researching, which led him to discover the neuroprotective benefits of methylene blue, validating Rick Rubin's earlier suggestion.

Elizabeth Iorns on Biotech Companies in YC
Y Combinator
Mentioned as an example of a disease where a biotech company might aim to develop a therapeutic intervention.

Dr. Peter Attia, MD — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show
Tim Ferriss
A neurodegenerative disease that impacted a close friend's parent, highlighting the importance of physical and cognitive health in old age.

How to Improve Brain Health & Offset Neurodegeneration | Dr. Gary Steinberg
Andrew Huberman
A neurodegenerative condition for which some studies suggest statins may reduce the risk of cognitive decline.

How to Focus to Change Your Brain
Andrew Huberman
Mentioned as a condition associated with degeneration of the nucleus basalis, potentially offset by nicotine use.

Neil Gaiman — The Interview I've Waited 20 Years To Do
Tim Ferriss
A neurodegenerative disease. Terry Pratchett faced his diagnosis publicly, making documentaries and bringing it into public consciousness. The host himself notes a family history of the disease.

The Kingdom of Sleep: A Conversation with Matthew Walker
Sam Harris
Discussed as a potential consequence of chronic sleep deficiency.
![Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]](https://i.ytimg.com/vi/HovRB26gbIg/maxresdefault.jpg)
Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]
Peter Attia MD
A neurodegenerative disease where genetic risk factors like APOE4 have been discussed.

Long COVID: All you need to know
Sabine Hossenfelder
A neurodegenerative disease for which virus exposure has been found to be associated with an increased risk.

257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies
Peter Attia MD
A common neurodegenerative disease, a subtype of dementia characterized by an accelerated cognitive decline.

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia
Peter Attia MD
A neurodegenerative disease that a new CETP inhibitor might also help treat.

248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation & main themes
Peter Attia MD
One of the 'Horsemen' diseases discussed, for which effective treatments are currently lacking but there's hope for better prevention data and clarity on things that reduce risk like exercise and sleep.

LIVE EVENT Q&A: Dr. Andrew Huberman at the Brisbane Convention & Exhibition Centre
Andrew Huberman
Neurologic disease mentioned as potentially being offset by nicotine use, according to an anecdote from a Nobel Prize winner.

LIVE EVENT Q&A: Dr. Andrew Huberman at the ICC Sydney Theatre
Andrew Huberman
Mentioned as a potential condition that keeping neuromodulator levels elevated might offset.

234 ‒ Chris Hemsworth on Limitless, longevity, and happiness
Peter Attia MD
A neurodegenerative disease for which carrying two copies of the APOE4 gene increases risk significantly, prompting a focus on brain health and risk mitigation.

Michael Levin: Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots | Lex Fridman Podcast #325
Lex Fridman
A neurodegenerative disease, mentioned in the context of regenerative medicine, where stem cell transplants could potentially generate specific types of neurons to treat such conditions.

Dr. Matt Walker: The Biology of Sleep & Your Unique Sleep Needs | Huberman Lab Guest Series
Andrew Huberman
A neurodegenerative disease for which deep sleep is critical in 'de-risking' the trajectory by clearing toxic proteins.

212 - The Neuroscience of Obesity | Peter Attia, M.D. & Stephan Guyenet, Ph.D.
Peter Attia MD
A neurodegenerative disease that Stephan Guyenet's grandmother had, which influenced his initial research interests, but he ultimately focused on a different class of neurodegenerative diseases during his PhD.

My Geriatric Medicine Placement - Junior Doctor Vlog #02
Ali Abdaal
A specific form of dementia characterized by progressive cognitive decline.

Demis Hassabis: DeepMind - AI, Superintelligence & the Future of Humanity | Lex Fridman Podcast #299
Lex Fridman
A disease potentially caused by misfolded proteins, highlighting the importance of understanding protein structures.