Ketogenic Diet

Cognitive Decline Expert: The Disease That Starts in Your 30s but Kills You in Your 70s

The Diary Of A CEO

A diet that promotes the production of ketone bodies, which the brain can use as an alternative fuel source when glucose metabolism is impaired, as seen in Alzheimer's patients and during perimenopause.

#48–Matt Walker, Ph.D., on Sleep (Part 2 of 3): Heart disease, cancer, causes of sleep disruption...

Peter Attia MD

Discussed in relation to fertility, with a hypothesis that it could negatively impact women's fertility by raising FGF21, which inhibits FSH, although metabolic benefits might offset this in some individuals.

Genes & the Inheritance of Memories Across Generations | Dr. Oded Rechavi

Andrew Huberman

A diet commonly known for increasing ketones, mentioned as a background for understanding the benefits of ketone supplementation for brain and body fuel.

175 - The biology of aging, rapamycin, and other interventions that target the aging process

Peter Attia MD

A nutritional strategy suggested as a treatment for Type 2 Diabetes due to its carbohydrate restriction, but not necessarily optimal for prevention, illustrating the difference between treating and preventing disease.

#163 - Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training

Peter Attia MD

A diet low in carbohydrates, often the subject of debate regarding its effects on muscle growth and exercise performance.

The Science of Psychedelics for Mental Health | Dr. Robin Carhart-Harris

Andrew Huberman

A dietary approach known to increase blood ketones, mentioned in the context of Ketone-IQ's benefits even for those not strictly adhering to it.

Q&A on Zone 2 Exercise with Peter Attia, M.D.

Peter Attia MD

Mentioned as a contrast to fasting, highlighting how different dietary approaches yield different physiological states.

No. 1 Sugar Expert: You've Been Sold A Lie About "Healthy" Food!

The Diary Of A CEO

Control Stress for Healthy Eating, Metabolism & Aging | Dr. Elissa Epel

Andrew Huberman

A diet that involves increasing blood ketones, mentioned in contrast to using Ketone-IQ as a supplement without strictly following the diet.

#144 - Phil Maffetone: Optimizing health and performance through maximal aerobic function

Peter Attia MD

A very low-carbohydrate diet discussed in the context of its potential effects on athletic performance and fat oxidation.

Andrew Huberman: Sleep, Dreams, Creativity, Fasting, and Neuroplasticity | Lex Fridman Podcast #164

Lex Fridman

A diet that involves low carbohydrate intake, leading to the body switching to ketosis for energy, which can enhance alertness and physical performance.

#37 – Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time

Peter Attia MD

A very low-carb, high-fat diet that Peter Attia followed and did well on but found unsustainable due to missing other foods.

#38–Francisco Gonzalez-Lima, Ph.D.: Alzheimer’s disease & the vascular hypothesis

Peter Attia MD

A dietary approach that facilitates mitochondrial respiration by providing ketone bodies as an alternative energy source for the brain, whose uptake is not compromised during aging unlike glucose.

#33 – Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin

Peter Attia MD

A very low-carbohydrate, high-fat diet that has shown anecdotal success in managing hyperphagia and cognitive aspects in children with Prader-Willi syndrome, and is associated with satiety for obese patients.

#31 – Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease

Peter Attia MD

A diet that may have benefits for the brain but can cause short-term insulin resistance in muscles.

Capsaicin, Multivitamins, and Time Off (Episode 60)

Stronger By Science

A diet critically reviewed for its effectiveness in gaining muscle, with meta-analyses showing it may lead to fat loss and lower lean body mass gains compared to non-ketogenic diets, often due to reduced appetite and palatability issues.

#28–Mark & Chris Bell: steroids, powerlifting, addiction, diet, training, & helping others live well

Peter Attia MD

Chris Bell discusses how he is conflicted about his diet and is trying to find answers, suggesting he's open-minded about it. Later, he notes its effectiveness for him in burning off hunger and cravings, and its historical use in bodybuilding for leanness.

Results from Peter's 3 week "nothingburger" (1 week keto—1 week fast—1 week keto) (AMA #2)

Peter Attia MD

The experiment involved periods on a ketogenic diet, which the speaker found led to increased LDL P, reduced IGF (over longer periods), and a hit to peripheral thyroid function.

Understanding & Conquering Depression

Andrew Huberman

A dietary approach that shifts brain metabolism to ketones, shown to reduce epileptic seizures and potentially aid in maintaining euthymia in bipolar individuals and providing relief for refractory major depression by increasing GABA transmission.

How to Improve at Learning Using Neuroscience & AI | Dr. Terry Sejnowski

Andrew Huberman

A dietary approach being explored for its potential to treat schizophrenia by impacting metabolic health of the brain and body.

Zach Bitter: Ultramarathon Running | Lex Fridman Podcast #205

Lex Fridman

A dietary approach that emphasizes very low carbohydrate intake, promoting fat metabolism, and potentially having therapeutic uses for mental conditions like depression and PTSD.

#69 – Ronesh Sinha, M.D.: Insights from a patient population predisposed to metabolic syndrome

Peter Attia MD

A very low-carbohydrate eating plan, mentioned by Peter Attia in the context of his own ability to regulate intake of purely ketogenic foods.

#14 – Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system

Peter Attia MD

A low-carbohydrate, high-fat diet that shifts the body's fuel source to ketones, discussed as an alternative to carbohydrate-based performance fuel.

The New Frontiers of Mental Health — Brain Stimulation, Rapid-Acting Tools for Depression, and More

Tim Ferriss

A diet low in carbohydrates and high in fat, suggested as a potential 'accelerated TMS equivalent' for certain psychiatric conditions, demonstrating remarkable transformations in some patients.