Essential Fructosuria
Concept
A hereditary condition where individuals lack fructokinase, causing them to excrete about 10% of ingested fructose in urine and metabolize the rest via glucose enzymes. People with this condition have not been reported to develop type 2 diabetes or obesity.
Mentioned in 2 videos
Videos Mentioning Essential Fructosuria

How Fructose Drives Metabolic Disease | Rick Johnson, M.D.
Peter Attia MD
A hereditary condition where individuals lack fructokinase, causing them to excrete about 10% of ingested fructose in urine and metabolize the rest via glucose enzymes. People with this condition have not been reported to develop type 2 diabetes or obesity.

#87—Rick Johnson, MD: Fructose—the common link in hypertension, insulin resistance, T2D, & obesity?
Peter Attia MD
A rare genetic condition where individuals are born without active fructokinase, making them almost immune to the metabolic harms of sugar.