COX-2
Concept
An enzyme that is a bottleneck in the inflammatory response; NSAIDs and aspirin inhibit it, which can then reduce hypertrophy signaling, especially in healthy young subjects.
Mentioned in 3 videos
Videos Mentioning COX-2

Season Finale: Tons of New Meta-Analyses and Q&A Catch-Up (Episode 46)
Stronger By Science
An enzyme that is a bottleneck in the inflammatory response; NSAIDs and aspirin inhibit it, which can then reduce hypertrophy signaling, especially in healthy young subjects.

Advil, Aspirin, and Tylenol -- What's the difference?
Sabine Hossenfelder
One of the two varieties of COX enzymes that NSAIDs block. Blocking COX-2 is thought to be primarily responsible for pain relief.

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)
Tim Ferriss
An enzyme involved in inflammation and pain, inhibited by NSAIDs, leading to reduced prostacyclin and nitric oxide production, and potential mitochondrial dysfunction.