SIRT1

Concept

A 'longevity gene' that resveratrol and tereselbeane were thought to activate, but evidence for this is questioned.

Mentioned in 4 videos

Videos Mentioning SIRT1

How To Boost NAD Levels To Fight Inflammation, Improve Recovery, and Slow Aging

How To Boost NAD Levels To Fight Inflammation, Improve Recovery, and Slow Aging

FoundMyFitness

A 'longevity gene' that resveratrol and tereselbeane were thought to activate, but evidence for this is questioned.

The Biology of Slowing & Reversing Aging | Dr. David Sinclair

The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Andrew Huberman

A specific sirtuin gene that is activated by low insulin and insulin-like growth factor levels, crucial for longevity.

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

Peter Attia MD

A transcriptional regulator that utilizes NAD+ as a cofactor, upstream of PTC1 alpha, playing a role in mitochondrial biogenesis.

David Sinclair: Extending the Human Lifespan Beyond 100 Years | Lex Fridman Podcast #189

David Sinclair: Extending the Human Lifespan Beyond 100 Years | Lex Fridman Podcast #189

Lex Fridman

A sirtuin gene related to Sir2, which when manipulated in animal brains, led to extended lifespan, highlighting the brain's central role in longevity.