Niemann-Pick C1-like 1 (NPC1L1) transporter

Concept

A specific transporter protein in the gut that is targeted by the drug ezetimibe to block cholesterol reabsorption.

Mentioned in 2 videos

Videos Mentioning Niemann-Pick C1-like 1 (NPC1L1) transporter

#96–David Epstein: How range of experience leads to better performance in a highly specialized world

#96–David Epstein: How range of experience leads to better performance in a highly specialized world

Peter Attia MD

A specific transporter protein in the gut that is targeted by the drug ezetimibe to block cholesterol reabsorption.

#19 – Dave Feldman: stress testing the lipid energy model

#19 – Dave Feldman: stress testing the lipid energy model

Peter Attia MD

A protein responsible for the absorption of cholesterol and phytosterols from the diet into the enterocytes (intestinal cells). Deficiencies can lead to increased cholesterol.