J20 Mouse Model

Concept

An aggressive mouse model of Alzheimer's disease that expresses human APP with mutant forms, leading to early synaptic loss and cognitive deficits.

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303-A breakthrough in Alzheimer’s disease: potential of klotho for brain health & as a therapeutic

303-A breakthrough in Alzheimer’s disease: potential of klotho for brain health & as a therapeutic

Peter Attia MD

An aggressive mouse model of Alzheimer's disease that expresses human APP with mutant forms, leading to early synaptic loss and cognitive deficits.