Insulin-like Growth Factor 1

Concept

A hormone whose signaling pathway, along with growth hormone, is impaired in 60% of centenarians, suggesting its role in human longevity via a delicate balance that changes with age.

Mentioned in 2 videos

Videos Mentioning Insulin-like Growth Factor 1

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

Peter Attia MD

A hormone whose signaling pathway, along with growth hormone, is impaired in 60% of centenarians, suggesting its role in human longevity via a delicate balance that changes with age.

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)

Dr. Rhonda Patrick Returns | The Tim Ferriss Show (Podcast)

Tim Ferriss

A hormone mediating many effects of growth hormone, activating the mTOR pathway for protein synthesis and essential for muscle growth. High levels are linked to increased cancer risk, but exercise can lower circulating IGF-1.