Daf-16

Concept

A gene mutation in C. elegans, an analog of FoxO3a/3b, which blocks the lifespan-extending effect of Daf-2 mutations when combined, indicating interaction.

Mentioned in 2 videos

Videos Mentioning Daf-16

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

Peter Attia MD

A gene discovered in Cynthia Kenyon's screen, a transcription factor associated with the IGF-1 receptor signaling pathway, manipulated to extend lifespan in C. elegans.

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

Peter Attia MD

A gene mutation in C. elegans, an analog of FoxO3a/3b, which blocks the lifespan-extending effect of Daf-2 mutations when combined, indicating interaction.