ATP-binding cassette G5/G8

Concept

Genes whose loss-of-function mutations lead to increased plant sterols in circulation and can cause sitosterolemia, a rare lipid disorder.

Mentioned in 2 videos

Videos Mentioning ATP-binding cassette G5/G8

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia

255-Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease, familial hypercholesterolemia

Peter Attia MD

Genes whose loss-of-function mutations lead to increased plant sterols in circulation and can cause sitosterolemia, a rare lipid disorder.

#19 – Dave Feldman: stress testing the lipid energy model

#19 – Dave Feldman: stress testing the lipid energy model

Peter Attia MD

A transporter protein in enterocytes that effluxes excess cholesterol and phytosterols back into the intestinal lumen. Deficiencies can lead to hypercholesterolemia.