Aldose reductase
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The rate-limiting enzyme in the polyol pathway that converts glucose to sorbitol. It is normally low in the liver but can be induced by high glucose, high uric acid, and increased serum osmolality.
The rate-limiting enzyme in the polyol pathway that converts glucose to sorbitol. It is normally low in the liver but can be induced by high glucose, high uric acid, and increased serum osmolality.