Acetyl-CoA
Concept
An end product of fatty acid beta-oxidation that allosterically regulates pyruvate carboxylase, crucial for gluconeogenesis. Its concentration in the liver tracks perfectly with rates of gluconeogenesis.
Mentioned in 2 videos
Videos Mentioning Acetyl-CoA

#140 - Gerald Shulman, MD, PhD: Insulin resistance—molecular mechanisms and clinical implications
Peter Attia MD
An end product of fatty acid beta-oxidation that allosterically regulates pyruvate carboxylase, crucial for gluconeogenesis. Its concentration in the liver tracks perfectly with rates of gluconeogenesis.

#21 – Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics and cholesterol regulation
Peter Attia MD
A two-carbon molecule that serves as the starting point for cholesterol synthesis in cells. It undergoes a multi-step process to grow and form the complex structure of cholesterol.